A group of 64 adults with all five components of metabolic syndrome received 150 mg of Pycnogenol a day for six months; a comparable group of 66 people served as unsupplemented controls.20 At the end of the study, the supplemented patients had significantly lower triglycerides and blood pressure, and significantly higher HDL cholesterol compared to controls. In addition, fasting glucose fell significantly by 14.4%, waist circumference dropped 3.11 inches (7.4%) in men and 2.9 inches ( 8%) in women, and plasma free radicals fell by 34.6% in the supplemented group