#p72317,Lakshmi написал(а):Так что, не будут они лежать..
Из книжки "The Art and Science of Low Carbohydrate LIVING" Phinney & Volek
At rest, skeletal muscles prefer fat
for fuel, using glucose only when insulin levels are high
and blood sugar needs some place to go. During
sustained exercise, fat is still the preferred fuel at
intensities up to 50-60% of that muscle’s maximum
continuous effort. Above 60% of maximum effort,
glucose (or stored glycogen) progressively assumes a
dominant role, although this dominance is attenuated
when individuals are given a few weeks to adapt to a
low carbohydrate diet[23, 27]. Also at these higher
intensities, some of this glucose is not completely
metabolized but is partially broken down to lactate and
released back into the bloodstream rather than being
oxidized in muscle mitochondria all the way to CO2 and
water. By contrast, during resistance exercise (very high
intensity, briefduration), most ofthe fuel use consists of
glucose made into lactate.
But here’s the interesting part. Lactate has a bad
reputation as a cause ofmuscle fatigue and pain. This is
a classic case of guilt by association. During transition
from rest to intense exercise, the increased production
of lactic acid rapidly disassociates into lactate and
hydrogen ion. It is the accumulation of hydrogen ion,
not lactate per se, that contributes to fatigue due to
acidosis. Lactate has a much more interesting and
positive role to play in the human body. Much of the
lactate released from muscle during exercise gets taken
up by the liver and made back into glucose (a process
called gluconeogenesis) and sent back to the muscles
where it can be made into lactate again. And because
the liver uses mostly fat to power gluconeogenesis, this
shuttle of glucose out from the liver and lactate back
(called the Cori cycle) actually ends up powering
resistance exercise from energy released by fat
oxidation in the liver.